Troubles with BoNT use in ophthalmology arise on account of toxin diffusion or inadvertent placement into the adjacent muscles. Ptosis in the eyelid is the most common complication of BoNT treatment of strabismus and blepharospasms.23 Despite the fact that this result is nearly always short-term and self-resolving, apraclonidine 0.5% (Iopidine) or